rs110419
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our findings revealed that rs110419 and rs2168101 polymorphisms were significantly associated with a decreased risk of NB in all genetic models.
|
31830377 |
2020 |
rs10840002
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In addition, the rs4758051 variant appeared protective against NB in homozygous, dominant and allele genetic models, whereas the rs10840002 variant markedly decreased the risk of NB in the allele model.
|
31830377 |
2020 |
rs204938
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In contrast, the rs204938 polymorphism showed a positive association with NB susceptibility in allele genetic models.
|
31830377 |
2020 |
rs4758051
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In addition, the rs4758051 variant appeared protective against NB in homozygous, dominant and allele genetic models, whereas the rs10840002 variant markedly decreased the risk of NB in the allele model.
|
31830377 |
2020 |
rs2168101
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our findings revealed that rs110419 and rs2168101 polymorphisms were significantly associated with a decreased risk of NB in all genetic models.
|
31830377 |
2020 |
rs217727
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we genotyped three SNPs (rs2839698 G>A, rs3024270 C>G, rs217727 G>A) from <i>H19</i> gene in a Chinese population (700 subjects with neuroblastoma and 1516 control subjects) enrolled from six hospitals and examined the effect of individual and combined SNPs on the risk of neuroblastoma.
|
31772668 |
2019 |
rs2839698
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we genotyped three SNPs (rs2839698 G>A, rs3024270 C>G, rs217727 G>A) from <i>H19</i> gene in a Chinese population (700 subjects with neuroblastoma and 1516 control subjects) enrolled from six hospitals and examined the effect of individual and combined SNPs on the risk of neuroblastoma.
|
31772668 |
2019 |
rs3024270
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we genotyped three SNPs (rs2839698 G>A, rs3024270 C>G, rs217727 G>A) from <i>H19</i> gene in a Chinese population (700 subjects with neuroblastoma and 1516 control subjects) enrolled from six hospitals and examined the effect of individual and combined SNPs on the risk of neuroblastoma.
|
31772668 |
2019 |
rs2273267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further independent case-control studies with functional analysis are needed to verify the role of NRAS gene rs2273267 A>T polymorphism in the risk of neuroblastoma.
|
31759987 |
2020 |
rs11247957
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein, we evaluated the correlation of four potentially functional LIN28A SNPs (rs3811464 G>A, rs3811463 T>C, rs34787247 G>A, and rs11247957 G>A) and neuroblastoma susceptibility in 505 neuroblastoma patients and 1070 controls from four independent hospitals in China.
|
31747721 |
2020 |
rs34787247
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, our finding indicated that LIN28A SNPs, especially rs34787247 G>A, may increase neuroblastoma risk.
|
31747721 |
2020 |
rs3811463
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein, we evaluated the correlation of four potentially functional LIN28A SNPs (rs3811464 G>A, rs3811463 T>C, rs34787247 G>A, and rs11247957 G>A) and neuroblastoma susceptibility in 505 neuroblastoma patients and 1070 controls from four independent hospitals in China.
|
31747721 |
2020 |
rs3811464
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein, we evaluated the correlation of four potentially functional LIN28A SNPs (rs3811464 G>A, rs3811463 T>C, rs34787247 G>A, and rs11247957 G>A) and neuroblastoma susceptibility in 505 neuroblastoma patients and 1070 controls from four independent hospitals in China.
|
31747721 |
2020 |
rs1052536
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that rs1052536 C>T and rs4796030 A>C are unrelated to neuroblastoma susceptibility in the Chinese population.
|
31737108 |
2019 |
rs4796030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that rs1052536 C>T and rs4796030 A>C are unrelated to neuroblastoma susceptibility in the Chinese population.
|
31737108 |
2019 |
rs28933981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cytotoxicity assays revealed their toxicities in the order of Val30Met > Ala97Ser > WT > Thr119Met in neuroblastoma cells.
|
31728576 |
2019 |
rs2153977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In vitro and in silico analyses indicated that the rs2153977-T protective allele, located in an NB and CMM enhancer, decreased expression of SLC16A1 via long-range loop formation and altered a T-box protein binding site.
|
31605138 |
2019 |
rs4938723
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Further investigation of how <i>miR-34b/c</</span>i> rs</span>4938723 T>C might modify neuroblastoma risk is warranted.
|
31583029 |
2019 |
rs12587
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a four-center case-control study to explore the association between <i>KRAS</i> gene polymorphisms (rs12587 G>T, rs7973450 A>G, rs7312175 G>A) and neuroblastoma susceptibility with 505 Chinese children and 1070 matched controls.
|
31564912 |
2019 |
rs7312175
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a four-center case-control study to explore the association between <i>KRAS</i> gene polymorphisms (rs12587 G>T, rs7973450 A>G, rs7312175 G>A) and neuroblastoma susceptibility with 505 Chinese children and 1070 matched controls.
|
31564912 |
2019 |
rs7973450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, our results suggested that rs7973450 A>G was associated with increased neuroblastoma risk.
|
31564912 |
2019 |
rs1386984902
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The present study aimed to evaluate the impact of the new TSPO ligands on mitochondrial dysfunction in a cellular model of AD-related tauopathy (human neuroblastoma cells SH-SY5Y stably overexpressing the P301L-mutant Tau) presenting mitochondrial impairments, including a decreased ATP synthesis and mitochondrial membrane potential, as well as a decrease in pregnenolone synthesis compared to control cells.
|
31536662 |
2020 |
rs1130409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we conducted a three-center case-control study to evaluate the association between <i>APEX1</i> polymorphisms (rs1130409 T>G, rs1760944 T>G, and rs3136817 T>C) and neuroblastoma risk in Chinese children, consisting of 469 cases and 998 controls.
|
31341530 |
2019 |
rs1760944
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we conducted a three-center case-control study to evaluate the association between <i>APEX1</i> polymorphisms (rs1130409 T>G, rs1760944 T>G, and rs3136817 T>C) and neuroblastoma risk in Chinese children, consisting of 469 cases and 998 controls.
|
31341530 |
2019 |
rs3136817
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we conducted a three-center case-control study to evaluate the association between <i>APEX1</i> polymorphisms (rs1130409 T>G, rs1760944 T>G, and rs3136817 T>C) and neuroblastoma risk in Chinese children, consisting of 469 cases and 998 controls.
|
31341530 |
2019 |